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KMID : 1101120180150020037
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Journal of Sleep Medicine
2018 Volume.15 No. 2 p.37 ~ p.42
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Effects of Transcranial Direct-Current Stimulation Therapy on Primary Chronic Insomnia: A Proof-of Concept Clinical Trial
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Jun Jin-Sun
Kim Tae-Joon
Koo Sun-A
Park Ji-Sook
Kim Keun-Tae
Yang Tae-Won
Lim Jung-Ah
Byun Jung-Ick
Sunwoo Jun-Sang
Jung Ki-Young
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Abstract
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Objectives: To assess the effect and safety of transcranial direct-current stimulation (tDCS) in primary chronic insomnia.
Methods: A one-month, double-blind, randomized, sham-controlled trial was performed. A total of 7 patients with primary chronic insomnia received tDCS using anodal (n=3), cathodal (n=2), or sham stimulation (n=2). They were followed up at 1 week and 1 month after treatment. The primary outcome measures included improvement in total sleep time (TST), sleep latency (SL), and sleep efficiency (SE) at 1 month follow-up.
Results: TST and SE were improved with tDCS at 1 month follow-up in all patients (100%) of the anodal group, one (50%) of the cathodal group, and one (50%) of the sham group. tDCS improved SL at 1 month follow-up in two patients (67%) of the anodal group, one (50%) of the cathodal group, and none (0%) of the sham group. With respect to adverse events, transient itching sensation occurred in one patient of the anodal group. None of the other groups reported adverse events.
Conclusions: Our results suggest that tDCS may be effective and safe for treatment of primary chronic insomnia. A larger controlled study needs to be further investigated.
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KEYWORD
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Primary chronic insomnia, Transcranial direct-current stimulation (tDCS), Non-pharmacological treatment
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